Reduced photoreceptor death and improved retinal function during retinal degeneration in mice lacking innate immunity adaptor protein MyD88.

In conclusion, lack of MyD88-mediated signaling increased photoreceptor survival and retina function in rd1 mice, which implicates MyD88-mediated innate immunity pathways as an important pathogenic factor during retinal degeneration.
PMID: 25725353 [PubMed - as supplied by publisher]

Source: Experimental Neurology - February 25, 2015 Category: Neurology Authors: Syeda S, Patel AK, Lee T, Hackam AS Tags: Exp Neurol Source Type: research