Sequencing the functional antibody repertoire—diagnostic and therapeutic discovery

Nature Reviews Rheumatology 11, 171 (2015).
doi:10.1038/nrrheum.2014.220

Author: William H. Robinson
The development of high-throughput DNA sequencing technologies has enabled large-scale characterization of functional antibody repertoires, a new method of understanding protective and pathogenic immune responses. Important parameters to consider when sequencing antibody repertoires include the methodology, the B-cell population and clinical characteristics of the individuals

Source: Nature Reviews Rheumatology - December 23, 2014 Category: Rheumatology Authors: William H. Robinson Tags: Review Source Type: research