Autoimmunity: Basophils in autoimmune and inflammatory diseases
Nature Reviews Rheumatology 11, 129 (2015).
doi:10.1038/nrrheum.2014.199
Authors: Meenu Sharma & Jagadeesh Bayry
Basophils are classically known for their pathogenic role in asthma and allergic skin conditions. However, reports suggest that basophil activation mediated by autoreactive IgE, thymic stromal lymphopoietin or Toll-like receptors has an important role in the pathogenesis of lupus nephritis, eosinophilic oesophagitis and IgG4-related diseases, respectively.
Source: Nature Reviews Rheumatology - Category: Rheumatology Authors: Meenu SharmaJagadeesh Bayry Tags: News and Views Source Type: research
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