Left Ventricular Diastolic Function Following Anthracycline-Based Chemotherapy in Patients with Breast Cancer without Previous Cardiac Disease-A Meta-Analysis

CONCLUSIONS: ANT had a modest early impact on E/A ratio, without changing EDT, e', or E/e' in patients with breast cancer without cardiac disease. Randomised studies on larger populations, using new parameters are required to define the role of diastolic dysfunction in the early diagnosis of ANT-induced cardiotoxicity.PMID:34501337 | DOI:10.3390/jcm10173890

Source: Clinical Breast Cancer - September 10, 2021 Category: Cancer & Oncology Authors: Raluca I Mincu Lena F Lampe Amir A Mahabadi Rainer Kimmig Tienush Rassaf Matthias Totzeck Source Type: research