Evaluation of the effects of atazanavir-ritonavir on the pharmacokinetics of lumefantrine in patients living with HIV in Lagos University Teaching Hospital, South-Western Nigeria

ConclusionATVr increased drug exposure and day 7 plasma concentration of lumefantrine. AL is therefore considered effective for the treatment of malaria in patients taking ATVr-based regimen. However, the safety associated with the interaction requires further elucidation.Trial registrationClinClinicalTrials.gov Identifier: NCT04531072, August 27, 2020. “Retrospectively registered”
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research