Population pharmacokinetic model of subcutaneous fentanyl in older acute care patients

ConclusionThis is the first report of subcutaneous fentanyl population pharmacokinetic model to evaluate fentanyl pharmacokinetic in older patients. The between subject variability in clearance and subcutaneous absorption rate was relatively high, and some patients recorded high fentanyl concentrations in the context of their titration to effect.
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research