Front Cover

Cover illustrationActivation of immune cells such as T-cells goes along with a massive reorganisation of molecules on the plasma membrane. To decipher these heterogeneities, the basal surface of activating T cells was imaged using spectrally resolved microscopy together with environment-sensitive membrane dyes. With spectral unmixing, maps of different spectral properties of emitted fluorescence were devised, allowing to determine the local lipid order around key membrane proteins. The cover image refers to the article “Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells” by I Urbančičet al. (pp. 2127-2146).
Source: FEBS Letters - Category: Biochemistry Tags: Issue Information Source Type: research