Hsa-circ_0003420 induces apoptosis in acute myeloid leukemia stem cells and impairs stem cell properties

CONCLUSIONS: Up-regulation of hsa-circ_0003420 expression in LSCs caused redox disorder, inflammation and apoptosis, suggesting that this protein could be used as a target for the treatment AML.PMID:34477035 | DOI:10.1080/08923973.2021.1963272

Source: Immunopharmacology and Immunotoxicology - September 3, 2021 Category: Allergy & Immunology Authors: Guoqiang Lin Yingying Fei Yanming Zhang Source Type: research