Irisin alleviates obesity-related spermatogenesis dysfunction via the regulation of the AMPK α signalling pathway

CONCLUSIONS: In conclusion, we found that irisin alleviated obesity-related spermatogenesis dysfunction via activation of the AMPKα signalling pathway. Based on these findings, we hypothesized that irisin is a potential therapeutic agent against obesity-related spermatogenesis dysfunction.PMID:34496874 | DOI:10.1186/s12958-021-00821-1

Source: Reproductive Biology - September 9, 2021 Category: Reproduction Medicine Authors: Yang Mu Huang-Guan Dai Ling-Bo Luo Jing Yang Source Type: research