NOD/scid IL ‐2Rγnull mice reconstituted with peripheral blood mononuclear cells from patients with Crohn's disease reflect the human pathological phenotype

ConclusionThe NSG-CD model partially reflects the human disease and allows for studying the development of fibrosis.

Source: Immunity, Inflammation and Disease - September 9, 2021 Category: Allergy & Immunology Authors: Anna ‐Lena Unterweger, Alena Rüscher, Marietta Seuß, Paula Winkelmann, Florian Beigel, Leandra Koletzko, Simone Breiteneicher, Matthias Siebeck, Roswitha Gropp, Attila Aszodi Tags: ORIGINAL ARTICLE Source Type: research