Immune dysregulation syndrome with cytotoxic T ‐lymphocyte antigen 4 mutation showing multiple central nervous system lesions

ConclusionsA patient withCTLA4 variant might develop multiple central nervous system lesions including longitudinally-extended spinal cord lesions. As there is effective targeted immunotherapy, a complete immunological work-up is required for early diagnosis when a patient presents with central nervous system lesions and multi-organ symptoms.

Source: Clinical and Experimental Neuroimmunology - September 8, 2021 Category: Neurology Authors: Makoto Eriguchi, Hiroo Katsuya, Keisuke Kidoguchi, Hiroshi Ureshino, Masanori Nishi, Masashi Nishihara, Motoshi Sonoda, Masataka Ishimura, Shinya Kimura, Hideo Hara Tags: CASE REPORT Source Type: research