Cortical, Spinal, Sacral, and Peripheral Neuromodulations as Therapeutic Approaches for the Treatment of Lower Urinary Tract Symptoms in Multiple Sclerosis Patients: A Review

DiscussionPTNS and SNM seem to be effective and safe therapeutic options for treating lower urinary tract symptoms in MS patients principally in case of overactive bladder (OAB) symptoms. Similarly, also SCS and TMS have been shown to be effective, despite the very limited number of patients and the small number of studies found in the literature. Interestingly, these techniques are effective even in patients who do not respond well to conservative therapies, such as anticholinergics. Furthermore, given their safety and efficacy, stimulations such as PTNS could be considered as a first-line treatment for OAB in MS patients, also considering that they are often preferred by patients to other commonly used treatments.

Source: Neuromodulation: Technology at the Neural Interface - September 9, 2021 Category: Biotechnology Authors: Martina Pericolini, Gabriel Miget, Claire Hentzen, Enrico Finazzi Agr ò, Camille Chesnel, Philippe Lagnau, Rebecca Haddad, Matthieu Grasland, Gerard Amarenco Tags: Review Article Source Type: research