Timing and Clinical Significance of Fluid Overload in Pediatric Acute Respiratory Distress Syndrome*

Conclusions: Fluid overload after day 4 of acute respiratory distress syndrome, but not before, was associated with worse outcomes. Higher angiopoietin-2 predicted subsequent fluid overload. Our results suggest that future interventions aimed at managing fluid overload may have differential efficacy depending on when in the time-course of acute respiratory distress syndrome they are initiated.
Source: Pediatric Critical Care Medicine - Category: Pediatrics Tags: Feature Articles Source Type: research