Long non-coding RNA RP11-490M8.1 inhibits lipopolysaccharide-induced pyroptosis of human umbilical vein endothelial cells via the TLR4/NF- κB pathway

CONCLUSIONS: These findings indicated that lncRNA RP11-490M8.1 inhibited LPS-induced pyroptosis via the TLR4/NF-κB pathway. Thus, lncRNA RP11-490M8.1 may provide a therapeutic target to ameliorate atherosclerosis.PMID:34469785 | DOI:10.1016/j.imbio.2021.152133

Source: Immunobiology - September 1, 2021 Category: Allergy & Immunology Authors: Xue-Hui Liu Li-Mei Wu Jia-Li Wang Xian-Hui Dong Shun-Chi Zhang Xue-Heng Li Hui Xu Da-Bin Liu Zhi-Hai Li Zhe-Ming Liu Shao-Guo Wu Yan-Wei Hu Source Type: research