Monophosphoryl lipid A directly regulates Th1 cytokine production in human CD4 < sup > + < /sup > T-cells through Toll-like receptor 2 and 4

CONCLUSION: These data provide evidence, at least in part, for the safe induction of an appropriate level of Th1 response by adjuvant MPLA in human vaccine development.PMID:34478947 | DOI:10.1016/j.imbio.2021.152132

Source: Immunobiology - September 3, 2021 Category: Allergy & Immunology Authors: Mousa Komai-Koma Yuan Ji Hui Cao Zhigang Liu Charles McSharry Damo Xu Source Type: research