Red blood cell distribution width and tumor necrosis factor- α for the early prediction of coronary artery lesion in Kawasaki disease: a retrospective study

Conclusion: In conclusion, alterations in RDW and TNF- α levels can be used as novel biomarkers for early prediction of CAL in KD patients, although the differences in their absolute values were small and might not give any added value to echocardiography.What is Known:•Known risk factors of CAL in children with KD include male gender and delayed use of intravenous immune globulin.What is New:•Our current study identified that red blood cell distribution width (RDW) and tumor necrosis factor-α (TNF-α) are novel independent risk factors for predicting CAL combined with KD among patients.•The combination of these RDW and TNF-α together shows higher sensitivity and specificity than either one used alone.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research