Glial cell line ‐derived neurotrophic factor and basic fibroblast growth factor derived from skeletal muscle pericytes increase the barrier function of endothelial cells in the endomysium

ConclusionGDNF and bFGF released from HSMPCTs increase the barrier function of endomysial endothelium. These HSMPCTs and TSM15 cells, which are recognized as anin vitro model of the endomysial capillary, might facilitate the analysis of the pathophysiology of the microvasculature in human skeletal muscle.

Source: Clinical and Experimental Neuroimmunology - September 6, 2021 Category: Neurology Authors: Eri Ishiguchi, Yasuteru Sano, Toshihiko Maeda, Fumitaka Shimizu, Miwako Fujisawa, Masaya Honda, Yukio Takeshita, Michiaki Koga, Takashi Kanda Tags: ORIGINAL ARTICLE Source Type: research