Genotoxicity and cytotoxicity of cone beam computed tomography in children

 BMC Oral Health volume 21, Article number: 427 (2021) detailsAbstractBackgroundDental radiographs are essential tools for diagnosis. However, there are significant concerns about the dangerous effect of radiation especially on children. The aim of this study was to evaluate genotoxicity and cytotoxicity in the exfoliated cells of buccal mucosa of children subjected to Cone Beam Computed Tomography (CBCT).MethodsThe study included 18 healthy children aged (9 –12 years) who were exposed to CBCT. All CBCT scans were performed with the i-CAT CBCT. Exfoliated buccal cells were scraped from the left and right cheek immediately before the exposure, after 10 ± 2 days, and after 1 month. Cells were stained using Feulgen/fast green stain and examined unde r light microscopy. Genotoxicity (Micronuclei) and cytotoxicity (condensed chromatin, karyorrhexis, pyknosis, and karyolysis) were scored. Statistical analysis was performed using the McNemar test, Wilcoxon Signed-Rank test, and Mann-Whitney U test at a significance level of p 
Source: Dental Technology Blog - Category: Dentistry Source Type: news

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This study compares the diagnostic accuracy of the ultra-low-dose CBCT (ULDCBCT) with that of the standard-dose CBCT (SDCBCT).Materials and methodsIn total, 64 patients were scanned with both the SDCBCT and the ULDCBCT protocols. Both studies were reported by two consultant radiologists with fellowship training in emergency radiology separated in time. The reporter recorded a diagnosis of fracture or normal and diagnostic confidence using a 5-point Likert scale. The gold standard was taken as the SDCBCT. Reporters were blinded to the indication and the SDCBCT report. Cases of discrepancy were resolved by consensus.ResultsT...
Source: Skeletal Radiology - Category: Radiology Source Type: research
J Neurosurg Spine. 2021 Nov 26:1-7. doi: 10.3171/2021.8.SPINE21901. Online ahead of print.ABSTRACTOBJECTIVE: The ability to utilize the T1 slope is often limited by poor visibility on cervical radiographs. The C7 slope has been proposed as a reliable substitute but may have similar limitations of visibility. Herein, the authors propose a novel method that takes advantage of the superior visibility on CT to accurately substitute for the radiographic T1 slope and compare the accuracy of this method with previously reported substitutes.METHODS: Lateral neutral standing cervical radiographs and cervical CT scans were examined....
Source: Journal of Neurosurgery.Spine - Category: Neurosurgery Authors: Source Type: research
Conclusions: In this retrospective review, most repeat CT scans had no new findings. A small percentage converted to positive, rarely altering clinical management. This study demonstrates the need for continued prospective research to update clinical guidelines that could reduce admission and serial CT scanning for mild TBI.PMID:34823406 | DOI:10.1177/00031348211063539
Source: The American Surgeon - Category: Surgery Authors: Source Type: research
J Neurosurg Spine. 2021 Nov 26:1-7. doi: 10.3171/2021.8.SPINE21901. Online ahead of print.ABSTRACTOBJECTIVE: The ability to utilize the T1 slope is often limited by poor visibility on cervical radiographs. The C7 slope has been proposed as a reliable substitute but may have similar limitations of visibility. Herein, the authors propose a novel method that takes advantage of the superior visibility on CT to accurately substitute for the radiographic T1 slope and compare the accuracy of this method with previously reported substitutes.METHODS: Lateral neutral standing cervical radiographs and cervical CT scans were examined....
Source: Journal of Neurosurgery.Spine - Category: Neurosurgery Authors: Source Type: research
Conclusions: In this retrospective review, most repeat CT scans had no new findings. A small percentage converted to positive, rarely altering clinical management. This study demonstrates the need for continued prospective research to update clinical guidelines that could reduce admission and serial CT scanning for mild TBI.PMID:34823406 | DOI:10.1177/00031348211063539
Source: The American Surgeon - Category: Surgery Authors: Source Type: research
Conclusions: We investigated and reported on the pathoanatomy of high-energy femoral neck fractures in young adults with the goal of increasing understanding of the injury and improving surgeons' ability to provide for improved treatment decisions and quality fracture repair. Level of Evidence: Diagnostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Source: Journal of Orthopaedic Trauma - Category: Orthopaedics Tags: Original Article Source Type: research
Conclusion: Combining the digital tomosynthesis technique with the portable x-ray machine could increase the diagnostic value for posterior pneumothoraces while avoiding intrahospital transport and limiting radiation exposure in comparison to CT scan.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Imaging Source Type: research
Background and Methods: To determine the extent and severity of complications of COVID-19, a single-center retrospective study was conducted on a cohort of 18 survivors who had chest CT scan upon admission and 10-12 weeks upon discharge. It included the measurement of pulmonary functions tests and a health status evaluation using SGRQ were done simultaneously during follow up.Results: Study has shown that they remained symptomatic with significant radiographic (pulmonary fibrosis) and alterations in lung functions, with mainly restrictive pattern (decrease DLCO and TLC) in severe illness group...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical respiratory physiology, exercise and functional imaging Source Type: research
Background: Despite the determination of maximal respiratory pressures (MRP) are not frequently evaluated in COPD, they are essential for the assessment of respiratory muscle dysfunction.Aims: To characterize the MRP according airway obstruction severity; To determine the odds ratio for radiographic and CT scan features and MRP reduction.Methods: Cross-sectional study. The sample included 73 COPD patients that performed lung function tests, 65 of those performed chest radiography and 67 CT scan. Airway obstruction was classified as mild, moderate and severe. The radiography criteria were diaphragm rectification, ribs horiz...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring airway disease Source Type: research
Conclusions: Mortality is associated with both the severity of illness and initial COVID related abnormal CXR; 58% have such changes at presentation and among the survivors having follow up radiology improves in two-thirds with approximately half the others then investigated by chest CT giving some indication to planning future services.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Clinical problems Source Type: research
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