Impact of rituximab on humoral response to COVID-19 booster vaccine and antibody kinetics in patients with ANCA vasculitis

The advent of vaccines has resulted in mitigation of severe disease as a consequence of SARS-CoV-2. There is notable absence of humoral absence after two doses of mRNA vaccines in rheumatic and musculoskeletal diseases. 1 There has been evidence that administration of third dose of vaccine leads to augmentation of humoral response in kidney transplant recipients. 2 In addition, there is increasing evidence that neutralizing antibody titers correlate with reduction in breakthrough infections in vaccinated individuals.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: letters to the editor Source Type: research