A two ‐year prospective study assessing the performance of fetal chromosomal microarray analysis and next‐generation sequencing in high‐risk pregnancies
ConclusionThe use of CMA in high-risk pregnancies is justified and provides relevant clinical information in 3.6% of the cases. NGS analysis in fetuses with multiple anomalies shows promising results, but more investigations are needed for a better understanding of practical applications of this molecular diagnosis method in prenatal settings.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Konstantin Ridn õi,
Kai Muru,
Maria Keernik,
Sander Pajusalu,
Eva‐Liina Ustav,
Pille Tammur,
Triin Mölter‐Väär,
Tiina Kahre,
Ustina Šamarina,
Karin Asser,
Ferenc Szirko,
Tiia Reimand,
Katrin Õunap Tags: ORIGINAL ARTICLE Source Type: research