Altered T cell subpopulations and serum anti-TYRP2 and tyrosinase antibodies in the acute and chronic phase of alopecia areata in the C3H/HeJ mouse model

Alopecia areata (AA) is an autoimmune disease resulting in non-scarring hair loss with an estimated lifetime incidence to be 2.1% in the USA for 20 years (1990 –2009) [1]. Although non-life-threatening, AA significantly reduces the life quality of patients compared with psoriasis or atopic dermatitis [2,3].

Source: Journal of Dermatological Science - September 3, 2021 Category: Dermatology Authors: Kei Hashimoto, Yoshihito Yamada, Mika Fujikawa, Kota Sekiguchi, Hideya Uratsuji, Sachi Mori, Hideki Watanabe, Tatsumi Matsumoto Source Type: research