Three ways to quickly lower your cholesterol levels – without relying on statins

HIGH cholesterol is the prerequisite to heart disease, a heart attack, or stroke - three life-threatening conditions. A free NHS health check - available from the age of 40 - can indicate where you're heading in life.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Older adults without heart disease shouldn’t take daily low-dose aspirin to prevent a first heart attack or stroke, an influential health guidelines group said in preliminary updated advice released Tuesday. Bleeding risks for adults in their 60s and up who haven’t had a heart attack or stroke outweigh any potential benefits from aspirin, the U.S. Preventive Services Task Force said in its draft guidance. For the first time, the panel said there may be a small benefit for adults in their 40s who have no bleeding risks. For those in their 50s, the panel softened advice and said evidence of benefit is less clear....
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthscienceclimate Research wire Source Type: news
In conclusion, premature thymic involution and chronic inflammation greatly contribute to increased morbidity and mortality in CKD patients. Mechanisms are likely to be multiple and interlinked. Even when the quest to fountain of youth is a pipe dream, there are many scientific opportunities to prevent or to, at least in part, reverse CKD-related immune senescence. Further studies should precisely define most important pathways driving premature immune ageing in CKD patients and best therapeutic options to control them. Extending Life Without Extending Health: Vast Effort Directed to the Wrong Goals https://www...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Doctors say inclisiran will prevent tens of thousands of deaths from heart attack and strokePatients in England are to start receiving a “gamechanger” drug that doctors say will protect tens of thousands of lives by cutting the number of people who have a heart attack or stroke.The treatment, inclisiran, works by boosting the liver ’s ability to reduce the body’s level of “bad” cholesterol, even in those who have already tried using statins.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Drugs Health Heart attack Stroke UK news NHS National Institute for Health and Care Excellence Source Type: news
In conclusion, our study demonstrated that elevated cumulative SBP or DBP was independently associated with increased risk of CVD in the Chinese population. Among participants with 15-year cumulative BP levels higher than the median, that is, 1970.8/1239.9 mmHg-year for cumulative SBP/DBP, which was equivalent to maintaining SBP/DBP level higher than 131/83 mmHg in 15 years, the CVD risk would increase significantly irrespective of whether or not the BP measurements at one examination was high. Our findings emphasize the importance of cumulative BP level in identifying individuals with high risk of CVD in the future. ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, phthalate exposure was positively associated with CVD in Chinese with type 2 diabetes. Type 2 diabetic men who are currently smoking, have an uncontrolled lipid profile, and are not using statins might be more susceptible to CVD when exposed to phthalates.PMID:34109519 | DOI:10.1007/s11356-021-14807-4
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Source Type: research
In this study, the research team designed a way to identify small molecules that improve the function of ABCA1 in the body while avoiding unwanted effects to the liver. The researchers honed in on a specific small molecule, CL2-57, due to its ability to stimulate ABCA1 activity with positive effects on liver and plasma triglycerides. The use of this compound showed improved glucose tolerance and insulin sensitivity, as well as reduced weight gain, among other beneficial effects. Age-Related Upregulation of Autophagy as a Possible Contribution to Bat Longevity https://www.fightaging.org/archives/2021/04/age-rela...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Epilepsy Behav. 2021 Mar 6;117:107878. doi: 10.1016/j.yebeh.2021.107878. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate whether cardiovascular risk, risk awareness, and guideline concordant treatment differ in individuals with versus without epilepsy.METHODS: This was a retrospective cross-sectional study using the National Health and Nutrition Examination Survey. We included participants ≥18 years for 2013-2018. We classified participants as having epilepsy if reporting ≥1 medication treating seizures. We calculated 10-year atherosclerotic cardiovascular disease (ASCVD) risk using the revised pooled cohort equ...
Source: Epilepsy and Behaviour - Category: Neurology Authors: Source Type: research
UK researchers seek to dispel concerns over pills prescribed for those at higher risk of heart attack and strokesStatins are generally not the cause of the muscle aches and pains that stop some people taking the pills prescribed to protect them against serious heart problems, according to a novel study that hopes to dispel some of the concerns.Two million people in the UK who are at higher risk of heart attack and strokes are eligible for statins, but many people refuse them or have stopped taking them because of sometimes alarming and widespread reports of muscle pain. But the study funded by the National Institute of Hea...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Statins Medical research Health Ageing UK news Heart attack Stroke Heart disease Science Society Source Type: news
In conclusion, long term LRIC could decrease blood pressure and ameliorate vascular remodeling via inflammation regulation. The Damage of a Heart Attack Causes the Immune System to Overreact https://www.fightaging.org/archives/2021/02/the-damage-of-a-heart-attack-causes-the-immune-system-to-overreact/ Researchers here note a mechanism that causes T cells of the adaptive immune system to spur chronic inflammation and tissue damage following a heart attack. As the researchers note, not all inflammation is the same. Some is maladaptive, and this is particularly the case in older individuals. The aged immune...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Abstract Background: Recent international guidelines have lowered recommended target levels of low-density lipoprotein-cholesterol (LDL-C) for patients at very high risk for major adverse cardiovascular events (MACE). However, uncertainty persists whether additional benefit results from achieved LDL-C levels below conventional targets. Inferences from prior analyses are limited because patients who achieve lower versus higher LDL-C on lipid-lowering therapy differ in other characteristics prognostic for MACE and because few achieved very low LDL-C levels. To overcome these limitations, we performed a propensity sc...
Source: Circulation - Category: Cardiology Authors: Tags: Circulation Source Type: research
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