Association between vedolizumab and postoperative complications in IBD: a systematic review and meta-analysis

ConclusionsOverall, compared with non-VDZ treatment, preoperative use of VDZ is relatively safer in adult IBD patients, which does not increase the risk of overall postoperative complications and reduces the occurrence of infectious complications. But, it increases the risk of all SSI and sSSI in infectious complications and the incidence of ileus and MCS in non-infectious complications. Due to lack of sufficient data, the safety of VDZ in pediatric patients is uncertain and requires further study.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research