Combined homologous recombination repair deficiency and immune activation analysis for predicting intensified responses of anthracycline, cyclophosphamide and taxane chemotherapy in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a clinically aggressive disease with abundant variants that cause homologous recombination repair deficiency (HRD). Whether TNBC patients with HRD are sensitive to anthr...

Source: BMC Medicine - September 1, 2021 Category: Internal Medicine Authors: Gaoming Liao, Zedong Jiang, Yiran Yang, Cong Zhang, Meiting Jiang, Jiali Zhu, Liwen Xu, Aimin Xie, Min Yan, Yunpeng Zhang, Yun Xiao and Xia Li Tags: Research article Source Type: research