Conditional uncertainty: Misinterpretations of “significant” p values
AbstractMisapplication ofp values can lead to very misleading conclusions.The frequent insignificance of a “significant” p value1provides examples illustrating situations wherep values are misused in interpretation and describes alternatives top values to consider. The concern aboutp values, and their potential shortcomings and misinterpretations, has been widely discussed and has received a lot of debate from the statistical community. While we agree with much of the content presented in the article, the issue fundamentally represents a misinterpretation of conditional probability, misapplication of measures regarding diagnostic accuracy, and consequently violations of assumptions inherent in experimental design and the validity of many approaches to statistical analysis and inference. One way this can be remedied is through team science, and collaboration between clinical and biostatistical scientists in research.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Shari Messinger Cayetano,
Alejandro Mantero Tags: COMMENTARY Source Type: research