Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology

CONCLUSIONS: Abuse exposure in girls is associated with a delayed structural maturation pattern specific to emotion circuitry, a potentially adaptive mechanism enhancing threat generalization. Physical neglect, on the other hand, is associated with a broader brain-wide pattern of advanced structural maturation. The differential influence of fronto-parietal cortices and the hippocampus on emotion circuit maturity in resilient girls may represent neurodevelopmental markers of reduced psychiatric risk following abuse.PMID:34407623 | DOI:10.1176/appi.ajp.2021.20081192

Source: The American Journal of Psychiatry - August 19, 2021 Category: Psychiatry Authors: Taylor J Keding Sara A Heyn Justin D Russell Xiaojin Zhu Josh Cisler Katie A McLaughlin Ryan J Herringa Source Type: research