Cystic ovarian teratoma as a novel tumor and growth hormone deficiency as new conditions presenting in Multiple Endocrine Neoplasia type 2B: Case reports and review of the literature

CONCLUSIONS: Improved awareness of nonendocrine signs of MEN2B could lead to earlier diagnosis, when surgical cure of MTC is possible. Alacrima is the first sign of MEN2B. We confirmed the possibility of growth retardation and GH deficiency in MEN2B, which had been previously rarely described. We suggest that patients with MEN2B may develop cystic ovarian teratoma, to the best of our knowledge, which has never been described so far in the literature. The results of this study could be used to guide further diagnosing of MENB2 at the early stage for better clinical outcome. We emphasize that MEN2B carries a risk for development of cystic ovarian teratoma as a novel tumor in this disease.PMID:34446941 | DOI:10.5507/bp.2021.051

Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 27, 2021 Category: Biomedical Science Authors: Renata Pomahacova Petra Paterova Eva Nykodymova Eliska Vaclavikova Pavla Sykorova Katerina Personova Ramir Katra Ivan Subrt Josef Sykora Source Type: research