Efficacy and safety of ketogenic dietary theraphies in infancy. A single-center experience in 42 infants less than two years of age.

Epilepsy is one of the major neurological disorders in childhood, and its incidence is higher during the first two years of life [1]. Seizure in infants may lead to severe cognitive problems and may seriously affect psychomotor developmentb [2]. In addition, some severe epileptic encephalopathies typically appear in the first months of life. Pharmacological treatment of epilepsy in infancy is often ineffective, and up to one third of infants may have drug resistant epilepsy. In this group of patients, the use of multiple ineffective antiseizure medicines (ASMs) may lead to progressive deterioration and the appearance of side effects that may worsen the patient's condition.
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research