Accuracy of Xpert Carba-R Assay for the Diagnosis of Carbapenemase-Producing Organisms from Rectal Swabs and Clinical Isolates: A Meta-Analysis of Diagnostic Studies

The Cepheid Xpert Carba-R assay has demonstrated a promising value for the detection of carbapenemase-producing organisms (CPOs), but its diagnostic performance remains unclear. Studies were retrieved from Cochrane Library, EMBASE and PubMed databases according to pre-determined selection criteria. The specificity, sensitivity, negative likelihood ratio, positive likelihood ratio and area under the summary receiver operating characteristic curves (AUC) of Xpert Carba-R were analyzed by STATA v13.0.
Source: Journal of Molecular Diagnostics - Category: Pathology Authors: Tags: Regular Article Source Type: research