Impact of using a lymph node revealing solution in surgical specimens for pathological staging of gastric cancer

Conclusion: The use of LRS in gastrectomy specimens is simple, enables dissection, increases the number of LNs, and occasionally changes pN staging and stage grouping. Introdução: O envolvimento do linfonodo (LNs) por metástase é importante critério para estadiar câncer gástrico (CG). Relaciona-se o prognóstico do CG com número de LNs metastáticos. Objetivos: Avaliar o impacto do uso de solução reveladora de linfonodos (SRL) em espécimes de gastrectomia. Materiais e métodos: Estudo prospectivo em 30 espécimes de gastrectomia (19 homens, média de idade 59,5 anos, e 11 mulheres, média de idade 66,1 anos) para estadiamento patológico tumor-linfonodo-metástase (TNM). Após dissecção dos LNs de acordo com procedimento de rotina (método convencional [MC]), esse tecido foi imerso em SRL, mistura contendo 65% de álcool, 20% de éter, 5% de ácido acético e 10% de formal a 10%, por 36 horas, com três mudanças, sendo realizada nova dissecção de LNs. Os LNs obtidos por ambos os métodos foram comparados e analisados. O número de LNs metastáticos e sem metástases foram determinados Resultados: Dissecados 1.005 LNs (33,5/caso): 657 LNs (21,9/caso) pelo MC e 348 LNs (11,6/caso) após uso da SRL (p = 0,0002). Metástases foram detectadas em 272...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research

Related Links:

ConclusionsLong-term OS in Indian patients in non-metastatic GC with EOX chemotherapy and D2 lymphadenectomy is similar to previously published Western data. Younger Indian patients fare worse than their older counterparts and this needs further evaluation.
Source: Journal of Gastrointestinal Cancer - Category: Cancer & Oncology Source Type: research
Bariatric surgery comprises a group of operative procedures designed to improve weight-related medical conditions. In the United States, these include vertical sleeve gastrectomy, Roux-en-Y gastric bypass, adjustable gastric banding, and the duodenal switch procedure. Bariatric surgery is the only durable and effective way for most humans to lose a significant amount of weight, and see improvement in obesity-related comorbidities. It can improve quality of life, prevent a number of cancers, and decrease overall mortality.
Source: Techniques in Vascular and Interventional Radiology - Category: Radiology Authors: Source Type: research
Authors: Okada K, Nishigori T, Obama K, Tsunoda S, Hida K, Hisamori S, Sakai Y Abstract Background: Visceral obesity is a risk factor for complications after gastrectomy in patients with gastric cancer. However, it is unclear whether postoperative complications decrease with preoperative reduction of visceral fat without the achievement of a nonobese state. This is because previous studies have performed categorical comparisons of obesity and nonobesity. The current study was performed to estimate the impact of the preoperative visceral fat area (VFA) as a continuous variable on postoperative complications after ga...
Source: Journal of Oncology - Category: Cancer & Oncology Tags: J Oncol Source Type: research
AbstractBackgroundCompletion total gastrectomy with radical lymphadenectomy for remnant gastric cancer is a technically demanding procedure. No previous studies have compared laparoscopic to robotic-assisted completion gastrectomy, whereas a few small case series have reported benefits of minimally invasive surgery over open surgery. The aim of this study is to assess the effectiveness and feasibility of robotic-assisted compared with laparoscopic completion gastrectomy for the treatment of remnant gastric cancer.MethodsWe retrospectively reviewed data from 55 patients who underwent minimally invasive completion gastrectom...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Hua Qiu, Jun-Hua Ai, Jun Shi, Ren-Feng Shan, Dong-Jun YuJournal of Cancer Research and Therapeutics 2019 15(7):1450-1463 Gastrectomy is considered the gold standard treatment for gastric cancer patients. Currently, there are two minimally invasive surgical methods to choose from, robotic gastrectomy (RG) and laparoscopic gastrectomy (LG). Nevertheless, it is still unclear which is superior between the two. This meta-analysis aimed to investigate the effectiveness and safety of RG and LG for gastric cancer. A systematic literature search was performed using PubMed, Embase, and the Cochrane Library databases until September...
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
ConclusionsOur findings clarified the feasibility of SN mapping based on the SN basin concept in patients with gastric cancer who previously underwent ER.
Source: Gastric Cancer - Category: Gastroenterology Source Type: research
Conclusions: This study demonstrates the positive long-term outcome of ESD for gastric neoplasia in a UK Caucasian population, encouraging further development and implementation of ESD in the UK. PMID: 31906741 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
An appropriate method of anastomosis is crucial for gastric cancer patients who require gastrojejunal anastomosis. Surgeons have proposed different types of modified gastrojejunostomies in the last two decades...
Source: BMC Surgery - Category: Surgery Authors: Tags: Research article Source Type: research
Conclusions: Our data show that the possibility of effective care also exists for Western patients with stage IV gastric cancer.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
ConclusionsE-stasis after LPPG occurs in 7.6% of patients. Age, DM, and intraabdominal infection are significantly related to E-stasis. E-stasis is associated with poorer nutritional and functional outcomes even at 1  year postoperatively.
Source: Gastric Cancer - Category: Gastroenterology Source Type: research
More News: Acetic Acid | Cancer | Cancer & Oncology | Gastrectomy | Gastric (Stomach) Cancer | Gastroenterology | Pathology | Study | Women