Microbial resistance and frequency of extended-spectrum beta-lactamase (ESBL) in isolated from blood cultures

Conclusion: The increase in the occurrence of ESBL in different Enterobacteriaceae shows the importance of the amplification of detection in other species than Escherichia coli or Klebsiella sp., so that the assistance to the patient is not restrained, since these resistant bacteria cannot be detected by the laboratories. Considering the frequency of ESBL in this study, we highlight the importance of its detection, aiming to its contribution to the development of improvements in the health care policies of hospitals. Introdução: A emergência e a disseminação dos isolados portadores de betalactamase de espectro estendido (ESBL) têm complicado o tratamento das infecções nosocomiais, uma vez que sua produção não é facilmente identificada nos testes de sensibilidade realizados rotineiramente em laboratórios clínicos, levando a dificuldades no controle hospitalar de microrganismos resistentes, bem como ao uso indevido de antibióticos. Objetivo: O objetivo deste trabalho foi analisar o perfil de resistência e a frequência de ESBL em bactérias Gram negativas isoladas de hemoculturas. Foram analisadas 100 amostras bacterianas, provenientes de hemoculturas de pacientes adultos, as quais foram identificadas fenotipicamente por provas bioquímicas de fermentação dos carboidratos e submetidas à determinação do perfil de resist&...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research

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Publication date: Available online 25 January 2020Source: Materials LettersAuthor(s): Yonglin Yu, Bailong Tao, Jinghui Sun, Lingling Liu, Hong ZhengAbstractBacterial-associated infection and poor osseointegration usually led to the failure of titanium (Ti)-based in orthopedic implantation. To solve above issues, a bioactive coating consisted of gelatin (Gel) and chitosan-graft-polyaniline (Chi-PANI) was fabricated with layer-by-layer (LBL) assembly technique on titanium dioxide nanotubes (TNT) substrates. Scanning electron microscopy (SEM), water contact angle (WCA) measurement X-ray photoelectron spectroscopy (XPS) and at...
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Source: Biochemical Engineering Journal - Category: Biochemistry Source Type: research
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