Anomeric effect, hyperconjugation and electrostatics: lessons from complexity in a classic stereoelectronic phenomenon

Chem. Soc. Rev., 2021, Advance Article DOI: 10.1039/D1CS00564B, Review ArticleIgor V. Alabugin, Leah Kuhn, Nikolai V. Krivoshchapov, Patricia Mehaffy, Michael G. Medvedev Like the tale of blind men and an elephant, discussions of the anomeric effect illustrate the danger of conclusions from a limited perspective. Stereoelectronic analysis addresses this challenge and remains the most useful in predicting reactivity. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Chemical Society Reviews - August 24, 2021 Category: Chemistry Authors: Igor V. Alabugin Source Type: research