Donor ‐derived M2 macrophages attenuate GVHD after allogeneic hematopoietic stem cell transplantation

ConclusionsWe showed the protective effects of donor-derived M2 macrophages on GVHD and improved survival in a model of HSCT. Our data suggest that donor-derived M2 macrophages offer the potential for cell-based therapy to treat GVHD.

Source: Immunity, Inflammation and Disease - August 19, 2021 Category: Allergy & Immunology Authors: Ryo Hanaki, Hidemi Toyoda, Shotaro Iwamoto, Mari Morimoto, Daisuke Nakato, Takahiro Ito, Kaori Niwa, Keishiro Amano, Ryotaro Hashizume, Isao Tawara, Masahiro Hirayama Tags: ORIGINAL ARTICLE Source Type: research