Obesity and Its Effects on the Esophageal Mucosal Barrier

In this report, we review mechanisms of esophageal mucosal defense, the genesis and remodeling of visceral adipose tissue during obesity, and the potential role of substances produced by VAT, especially the VAT that encircles the esophagogastric junction, in the impairment of esophageal mucosal barrier integrity that leads to the development of GERD complications.PMID:34405732 | DOI:10.1152/ajpgi.00199.2021

Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - August 18, 2021 Category: Physiology Authors: Shere L Paris Rebecca Ekeanyanwu Yuwei Jiang Daniel Davis Stuart Jon Spechler Rhonda F Souza Source Type: research