Very early glucose tolerance abnormalities in children with cystic fibrosis

Pancreatic injury in cystic fibrosis (CF) begins in utero, as evidenced by an increase in immunoreactive trypsinogen values in new-born screening. Cystic-fibrosis-related diabetes (CFRD), a comorbidity of CF, differs from Type 1 or Type 2 diabetes mellitus. It occurs primarily due to impaired insulin secretion and worsens prognosis, because it is associated with decreased lung function and poor nutritional status [1]. Dysglycaemia frequency increases over time amongst children, adolescents and young adults.
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research