Macrophage metabolic regulation in atherosclerotic plaque

Metabolism plays a key role in controlling immune cell functions. In this review we will discuss the diversity of plaque resident myeloid cells and will focus on their metabolic demands that could reflect on their particular intraplaque localization. Defining the metabolic configuration of plaque resident myeloid cells according to their topologic distribution could provide answers to key questions regarding their functions and contribution to disease development.

Source: Atherosclerosis - August 16, 2021 Category: Cardiology Authors: Bastien Dolfi, Alexandre Gallerand, Arvand Haschemi, Rodolphe R. Guinamard, Stoyan Ivanov Source Type: research