Adverse health outcomes in vitamin D supplementation trials for depression: a systematic review

CONCLUSIONS AND IMPLICATIONS: While depressed persons are at increased risk of vitamin D deficiency, supplementation trials hardly addressed the common negative health consequences of low vitamin D levels as secondary outcome measures. Well-designed trials of the effects of vitamin D supplementation in late-life depression should explore whether adverse health outcomes can be prevented or stabilised, and whether depression benefits from this improvement.PMID:34390851 | DOI:10.1016/j.arr.2021.101442

Source: Ageing Research Reviews - August 14, 2021 Category: Genetics & Stem Cells Authors: Karen S van den Berg Radboud M Marijnissen Rob H S van den Brink Richard C Oude Voshaar Johanna M Hegeman Source Type: research