The Impact of Deranged Glucose Metabolism and Diabetes in The Pathogenesis and Prognosis of The Novel Sars-Cov-2: A Systematic Review of Literature

CONCLUSION: A combination of underlying chronic conditions such as hypertension, obesity, and cardiovascular diseases together with altered ACE receptor expression, immune dysregulation via cytokine storm, alveolar and endothelial dysfunction, increased systemic coagulation may put individuals with diabetes at risk for COVID-19 severity. More studies are needed to elucidate how glucose-lowering drugs may modulate the host immune response in diabetic individuals, especially following the administration of potential COVID-19 vaccines.PMID:34365925 | DOI:10.2174/1573399817666210806104349
Source: Current Diabetes Reviews - Category: Endocrinology Authors: Source Type: research