Postoperative seizure and developmental outcomes of children with hemimegalencephaly and drug-resistant epilepsy

Hemimegalencephaly (HMEG) belongs to the brain overgrowth spectrum with unilateral megalencephaly involving one or almost one entire brain hemisphere [1]. Developmental delay, contralateral hemiparesis, and drug-resistant epilepsy are common in children with HMEG [2, 3]. Early epileptic seizures usually evolve into epileptic encephalopathies and lead to severe psychomotor retardation without intervention [4].

Source: Seizure: European Journal of Epilepsy - August 13, 2021 Category: Neurology Authors: Qingzhu Liu, Jiayi Ma, Guojing Yu, Qian Zhang, Ying Zhu, Ruofan Wang, Hao Yu, Chang Liu, Yu Sun, Wen Wang, Shuang Wang, Taoyun Jia, Ming Li, Xiaoyan Liu, Yuwu Jiang, Lixin Cai, Ye Wu Source Type: research