P –733 In infertile patients, risk factors for environmental reprotoxic exposure are widespread, limited in number and modifiable

AbstractStudy questionWhat are the risk factors for environmental reprotoxic exposure in infertile patients?Summary answerThe most represented categories of reprotoxic risk factors (RRF) were dietary exposures (86% of patients), overweight (46%), psychoactive substances (38%) and male occupational exposures (63%).What is known alreadyNumerous studies have reported the deleterious effects of environmental reprotoxic exposures on male or female fertility.These studies most often focus on the impact of a limited number of reprotoxic risk factors (body mass index (BMI), dietary habits, tobacco or alcohol consumption) or a limited number of chemical or physical reprotoxic exposures: phthalates, occupational exposures, or pesticides.Despite the call of several reproductive health professional societies and public health agencies for taking environmental health into account in women of childbearing age, this approach remains little realized in current practice.Study design, size, durationWe conducted a prospective, monocentric study between June 2018 and February 2020 in women and men visiting the fertility unit of our University Hospital for assisted reproduction technique (ART) treatment.Participants/materials, setting, methodsPatients completed a self-questionnaire to collect information about i) the various types of exposure to RRF, and ii) frequency and intensity of exposures (qualitative and semi-quantitative approach).We performed a literature search in order to define the en...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research