P –579 Pregnancies following preimplantation Genetic Testing have an increased risk for post-partum complications

AbstractStudy questionDo preimplantation genetic testing (PGT) pregnancies have higher pregnancy and delivery complications compared to naturally conceived (NC) pregnancies?Summary answerPGT pregnancies do not have increase pregnancy complications but do have increased post-partum complications.What is known alreadyThere is limited data about the outcome of PGT cycles regarding pregnancy complications.Previous reports show that PGT pregnancies are similar to NC pregnancies regarding birth weight and preterm delivery rate.Patients performing PGT are less likely to have infertility as a background problem, and therefore it is important to evaluate pregnancy complications in this specific population.Study design, size, durationA retrospective cohort study, between 2008 –2020 in Shaare Zedek Medical center (SZMC). Demographic, background variables, treatment cycle information, and delivery data were collected from computerized hospital databases and patient files.Participants/materials, setting, methodsAll patients aged 18 –45 that conceived following PGT treatment in the IVF unit and gave birth in SZMC were included in the study.We used two control groups: (1) women with spontaneous pregnancies (SP) who gave birth in SZMC. We used four “neighborhood control” for each PGT patient (two women delivered before and two after the case delivery). (2) pregnancies following ICSI with four neighborhood control for each.Main results and the role of chance135 deliveries following PG...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research