1,173 Cases of Domestic Arboviral Disease Reported in 2019 in United States

THURSDAY, Aug. 12, 2021 -- In 2019, there were 1,173 cases of domestic arboviral disease, of which 83 percent were West Nile virus (WNV) disease cases, according to research published in the Aug. 13 issue of the U.S. Centers for Disease Control and...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Transfus Clin Biol. 2021 Sep 22:S1246-7820(21)00474-2. doi: 10.1016/j.tracli.2021.09.008. Online ahead of print.ABSTRACTThe Secproch working group (for « sécurité des produits issus du corps humain ») was created in 2019 within the « Haut Conseil de la Santé Publique » (HCSP) for addressing all the questions related to labile blood products, organs, tissues, cells (OTC) and gametes issued from human body. It is notably in charge of the management of alerts regarding arbovirus infections. These infections due to arthropod-transmitted viruses are responsible for emergence and reem...
Source: Transfusion Clinique et Biologique - Category: Hematology Authors: Source Type: research
er T. Ciota West Nile virus (WNV, Flaviviridae, Flavivirus) is a mosquito-borne flavivirus introduced to North America in 1999. Since 1999, the Earth’s average temperature has increased by 0.6 °C. Mosquitoes are ectothermic organisms, reliant on environmental heat sources. Temperature impacts vector–virus interactions which directly influence arbovirus transmission. RNA viral replication is highly error-prone and increasing temperature could further increase replication rates, mutation frequencies, and evolutionary rates. The impact of temperature on arbovirus evolutionary trajectories and fitness lands...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Female Culex mosquito, courtesy: CDC Cases of West Nile virus, a mosquito-borne illness, have been reported across the U.S. It's the leading cause of mosquito-borne disease in the continental U.S., according to the Centers for Disease Control and Prevention (CDC)."We are currently seeing high levels of West Nile virus infection across many parts of the United States, including a higher number than normal of people with neuroinvasive disease ― the most severe form of infection,"…
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
The level of viremia and features of the course of experimental infection caused by West Nile virus were studied in two species of migratory birds, siskinsСarduelis spinus and quailsCoturnix coturnix, and in one species of amphibians, frogsRana ridibunda. In quails, the virus caused a fatal disease; histological analysis revealed pathological changes in the heart, kidneys, liver, and brain stem. In siskins and frogs, virus antigen was detected in cloacal smears despite the absence of clinical manifestations, the level of viremia was sufficient to infect insect vectors during bloodsucking. These findings suggest that siski...
Source: Bulletin of Experimental Biology and Medicine - Category: Biology Source Type: research
owotny Cavalleri The emergence of West Nile virus (WNV) and Usutu virus (USUV) in addition to the autochthonous tick-borne encephalitis virus (TBEV) in Europe causes rising concern for public and animal health. The first equine case of West Nile neuroinvasive disease in Austria was diagnosed in 2016. As a consequence, a cross-sectional seroprevalence study was conducted in 2017, including 348 equids from eastern Austria. Serum samples reactive by ELISA for either flavivirus immunoglobulin G or M were further analyzed with the plaque reduction neutralization test (PRNT-80) to identify the specific etiologic agent. Ne...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
This study is the first report to show the circulation of WNV lineage 1 in donkeys in Turkey.
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
nelly Temperature plays a significant role in the vector competence, extrinsic incubation period, and intensity of infection of arboviruses within mosquito vectors. Most laboratory infection studies use static incubation temperatures that may not accurately reflect daily temperature ranges (DTR) to which mosquitoes are exposed. This could potentially compromise the application of results to real world scenarios. We evaluated the effect of fluctuating DTR versus static temperature treatments on the infection, dissemination, and transmission rates and viral titers of Culex tarsalis and Culex quinquefasciatus mosquitoes f...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Debra P. C. Peters Mosquito-borne West Nile virus (WNV) is the causative agent of West Nile disease in humans, horses, and some bird species. Since the initial introduction of WNV to the United States (US), approximately 30,000 horses have been impacted by West Nile neurologic disease and hundreds of additional horses are infected each year. Research describing the drivers of West Nile disease in horses is greatly needed to better anticipate the spatial and temporal extent of disease risk, improve disease surveillance, and alleviate future economic impacts to the equine industry and private horse owners. To help meet ...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Mast cell activators are a novel class of mucosal vaccine adjuvants. The polymeric compound, Compound 48/80 (C48/80), and cationic peptide, Mastoparan 7 (M7) are mast cell activators that provide adjuvant activity when administered by the nasal route. However, small molecule mast cell activators may be a more cost-efficient adjuvant alternative that is easily synthesized with high purity compared to M7 or C48/80. To identify novel mast cell activating compounds that could be evaluated for mucosal vaccine adjuvant activity, we employed high-throughput screening to assess over 55,000 small molecules for mast cell degranulati...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
by Alexander C. Keyel, Morgan E. Gorris, Ilia Rochlin, Johnny A. Uelmen, Luis F. Chaves, Gabriel L. Hamer, Imelda K. Moise, Marta Shocket, A. Marm Kilpatrick, Nicholas B. DeFelice, Justin K. Davis, Eliza Little, Patrick Irwin, Andrew J. Tyre, Kelly Helm Smith, Chris L. Fredregill, Oliver Elison Timm, Karen M. Holcomb, Michael C. Wimberly, Matthew J. Ward, Christopher M. Barker, Charlotte G. Rhodes, Rebecca L. Smith West Nile virus (WNV) is a globally distributed mosquito-borne virus of great public health concern. The number of WNV human cases and mosquito infection patterns vary in space and time. Many statistical models...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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