Development of a Heart Rate Variability Risk Score to Predict Organ Dysfunction and Death in Critically Ill Children

CONCLUSIONS: The Heart Rate Variability Dysfunction score, an age-adjusted proxy for autonomic nervous system dysregulation derived from bedside monitor data is independently associated with new or progressive multiple organ dysfunction syndrome and mortality in PICU patients. The Heart Rate Variability Dysfunction score could potentially be used as a single continuous physiologic biomarker or as part of a multivariable prediction model to increase awareness of at-risk patients and augment clinical decision-making.
Source: Pediatric Critical Care Medicine - Category: Pediatrics Tags: Online Clinical Investigation Source Type: research