19. Anterior lumbar interbody fusion with porous titanium interbody cages is associated with equivalent fusion rates and patient reported outcomes as bone morphogenetic protein-2

Although frequently used for anterior lumbar interbody fusion (ALIF), concerns regarding the use of recombinant human bone morphogenetic protein 2 (BMP-2) include off-label use, elevated cost and adverse outcomes such as osteolysis. The growing evolution of porous implant technology in promoting osseous integration via ingrowth provides an opportunity for a paradigm shift by relying less on biologic-assisted through-growth and leveraging implant on-growth and in-growth in similar fashion to porous metallic implants used in other orthopedic settings such as hip arthroplasty.

Source: The Spine Journal - August 11, 2021 Category: Orthopaedics Authors: Athan Zavras, Zakariah Siyaji, Ali Piracha, Talha Qadri, Unzila Manzoor, Syeda Qadri, Michael T. Nolte, Arash Sayari, Matthew Colman Source Type: research