Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target

Pancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to ...

Source: Journal of Experimental and Clinical Cancer Research - August 10, 2021 Category: Cancer & Oncology Authors: Silpa Gampala, Fenil Shah, Xiaoyu Lu, Hye-ran Moon, Olivia Babb, Nikkitha Umesh Ganesh, George Sandusky, Emily Hulsey, Lee Armstrong, Amber L. Mosely, Bumsoo Han, Mircea Ivan, Jing-Ruey Joanna Yeh, Mark R. Kelley, Chi Zhang and Melissa L. Fishel Tags: Research Source Type: research