Methotrexate and theaflavin-3, 3 ′-digallate synergistically restore the balance between apoptosis and autophagy in synovial fibroblast of RA: an ex vivo approach with cultured human RA FLS

ConclusionDisruption in homeostasis between apoptosis and autophagy infd-FLS might be an underlying phenomenon in the progression of pathophysiology in RA. Co-administration of MTX  + TF3 successfully restored the homeostasis by inducing apoptosis.
Source: Inflammopharmacology - Category: Drugs & Pharmacology Source Type: research