27989 An unusual presentation of acute generalized exanthematous pustulosis (AGEP) in pregnancy

A 39-year-old female at 23 weeks ’ gestation presented with a four-day history of diffuse pustules that developed acutely on her abdomen and rapidly spread. She denied any associated symptoms, personal or family history of skin disorders, and review of systems was negative. Her medications included omeprazole for gastroesophageal reflux disease and a prenatal vitamin. Physical examination revealed enumerable pustules over the abdomen and flanks with background erythema; erythematous macules and papules coalescing into edematous plaques with enumerable overlying pustules on the anterior lower extremities; scattered erythemat ous macules on the upper extremities; and rare pustules on the chest and neck.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research

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When Joe Silverman developed Crohn’s disease at age 21, the symptoms started out mild. While the sight of blood in his stools initially freaked him out, what really bothered him was the frequent abdominal pain and bloating that occurred as his condition progressed to moderate and then severe. Dietary changes didn’t make a difference, so he began taking prescription oral anti-inflammatory drugs that are often used to treat certain bowel diseases, which alleviated but didn’t eliminate his discomfort. He started using prescription steroid suppositories to cope with flare-ups of the inflammatory bowel disease...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: news
Am J Physiol Gastrointest Liver Physiol. 2021 Jun 9. doi: 10.1152/ajpgi.00480.2020. Online ahead of print.ABSTRACTSwallowing is a critical function for survival and development in human neonates, and requires cross-system coordination between neurologic, airway, and digestive motility systems. Development of pharyngo-esophageal motility is influenced by intra- and extra-uterine development, pregnancy complications, and neonatal comorbidities. Primary role of these motility reflex mechanisms is to maintain aerodigestive homeostasis under basal and adaptive biologic conditions including oral feeding, gastroesophageal reflux,...
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - Category: Physiology Authors: Source Type: research
A simple dietary modification could obviate the need for pharmacologic treatment of GERD in some women.Medscape Medical News
Source: Medscape Gastroenterology Headlines - Category: Gastroenterology Tags: Ob/Gyn & Women ' s Health News Source Type: news
Conclusions: We reported for the first time that short MTBT was a predominant risk factor of GERD in pregnancy. This dieting habit was significantly associated with reflux symptom frequency and reflux-related insomnia.
Source: Journal of Clinical Gastroenterology - Category: Gastroenterology Tags: Alimentary Tract: Original Articles Source Type: research
Abstract Gastroesophageal reflux disease (GERD) is a common digestive disorder that causes esophagitis and injuries to the esophageal mucosa. GERD symptoms are recurrent during pregnancy and their treatment is focused on lifestyle changes and nonprescription medicines. The aim of this study was to characterize the mechanism of action of a new patented medical device, an oral formulation containing hyaluronic acid, rice extract, and amino acids dispersed in a bioadhesive polymer matrix, by assessing its protective effects in in vitro and ex vivo models of esophageal mucosa damage. Acidic bile salts and pepsin cockt...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
Abstract The long-term use of proton pump inhibitors (PPIs) can lead to increased gastric pH, hypochlorhydria and in some cases to achlorhydria when compared to other acid-suppressing agents like histamine-2 (H2) receptor blockers and antacids. These consequences by the use of long-term PPIs may lead to significant vitamin (B12 and C) and mineral (iron, calcium and magnesium) deficiencies which needs gastric acid for their absorption and bioavailability. Long-term use of PPIs by the pregnant patients may impose a potential risk of congenital malformations. Various studies have recommended the life style modificati...
Source: Therapie - Category: Psychiatry & Psychology Authors: Tags: Therapie Source Type: research
CONCLUSION: GERD is more important than periodontitis for predicting and preventing preterm birth. For preventing preterm birth, preventive measures for hypertension, GERD and diabetes mellitus would be needed alongside the promotion of effective BMI management and appropriate progesterone and calcium-channel-blocker medications. PMID: 32281316 [PubMed - in process]
Source: J Korean Med Sci - Category: General Medicine Authors: Tags: J Korean Med Sci Source Type: research
Uterine fibroids affect up to 80% of reproductive-aged women. Although many women are asymptomatic, fibroids can cause pelvic pain, abnormal uterine bleeding, anemia, urinary frequency, infertility, and adverse pregnancy outcomes that can impair quality of life. Fifty percent of women with symptomatic fibroids report a detrimental impact on their mental and physical health (1). Fibroids appear to have a greater impact on quality of life than other chronic conditions, including asthma, irritable bowel syndrome, and gastroesophageal reflux disease (2).
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
Do you feel under the weather but don’t want to go to the doctor yet? Are you searching for a solution to inform yourself about any possible condition from the comfort of your home and with the ease of your phone or computer? Of course, there’s an app for that! Not only one, but numerous. Join us as we test how well several services perform at gauging possible diagnoses based on one’s signs and symptoms. We entrust our diagnosis with the Mayo Clinic, WebMD, Your.MD,Symptomate and Ada symptom checker services. Here’s our big symptom checker review. The age of symptom checkers Are you feeling na...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine Telemedicine & Smartphones diagnostics doctor Health Healthcare home patient primary care review smart medicine smartphone apps symptom symptom checker technology Source Type: blogs
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