28581 Vulvar mammary-like adenocarcinoma with overlying extramammary Paget disease
Observations: An 88-year old Asian female with a history of thyroid cancer presented with an itchy 5 cm erythematous inflammatory plaque on the right labia majora extending to the clitoris and left labia majora. Biopsy revealed mammary-like adenocarcinoma beneath extramammary paget disease of the vulva. Breast mammograms revealed no malignancy. The invasive dermal tumor resembled invasive ductal adenocarcinoma of the breast, being positive for cytokeratin 7 and negative for cytokeratin 20. Malignant pagetoid cells were in the epidermis.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Betty Nguyen, Lauren Michelle, Cyrus Nguyen, Larisa Lehmer, Bruce D. Ragsdale Source Type: research
More News: Academies | Adenocarcinoma | Cancer | Cancer & Oncology | Dermatology | Itchiness | Mammography | Paget Disease of the Nipple | Paget's Disease | Skin | Thyroid | Thyroid Cancer | Vulvar Biopsy