Pain relief reverses hippocampal abnormalities in trigeminal neuralgia

Chronic pain adversely affects cognitive performance and significantly impacts quality of life 58,63. Chronic pain patients frequently experience poor memory and concentration, often accompanied by increased anxiety and depression 3,8,14,15,23,35 –37,40,57,64,66–68,74,75,82,85,90,102. The hippocampal formation consists of anatomically and functionally distinct subfields including the subiculum, Cornu Ammonis (CA1 – CA4), and dentate gyrus (DG). These subcortical regions play a significant role in memory formation 51, emotional processi ng, and stress modulation 103.
Source: The Journal of Pain - Category: Materials Science Authors: Tags: Original Reports Source Type: research