Ischemic heart failure mortality is not predicted by cardiac insulin resistance but by diabetes perse and coronary flow reserve: A retrospective dynamic cardiac 18F-FDG PET study

Background& aims.The connection between peripheral insulin resistance (IR) and coronary artery disease is well-established. Both are major risk factors for the development of ischemic cardiomyopathy potentially leading to heart failure (HF). Whether cardiac IR also impacts overall survival and morbidity is still debated. We therefore aimed to test if cardiac IR predicts mortality and major cardiovascular events (MACE) in patients with HF scheduled for cardiac viability testing before revascularization.

Source: Metabolism - Clinical and Experimental - August 7, 2021 Category: Biomedical Science Authors: Thien Vinh Luong, Mette Glavind B ülow Pedersen, Mette Louise Blouner Gram Kjærulff, Simon Madsen, Katrine Meyer Lauritsen, Lars Poulsen Tolbod, Esben Søndergaard, Lars C. Gormsen Source Type: research